Canine Genetics and Epidemiology is a peer-reviewed, open access, online journal publishing original research and review articles relating to all aspects of canine genetics and epidemiology.
- Gustavo Aguirre, University of Pennsylvania
- Bill Ollier, University of Manchester
- Lorna Kennedy, University of Manchester
The Kennel Club Educational Trust will cover 50% of the article processing charge for manuscripts published in the area of domestic dog health. Please contact firstname.lastname@example.org for more information.
Using massive parallel sequencing of DNA from dogs and wolves, the authors have found 155 new genetic variants of canine Toll-like receptors, primary sensors of pathogens in the body.
Canine degenerative myelopathy (CDM) is a progressive disease affecting the spinal cord of dogs. This article presents a DNA "fingerprint" assay to test for the SOD1 mutation associated with susceptibility to CDM.
The authors identified two significant risk factors associated with Chiari-like malformation/syringomyelia in the skull shape of the Cavalier King Charles Spaniel: extent of brachycephaly and distribution of doming of the cranium.
This study examined 18 genes associated with human monogenic diabetes, and tested whether they are also associated with diabetes in 17 different dog breeds. Six variants from five genes were associated with diabetes in some breeds, including two variants in ZFP57 associated with diabetes in two different breeds.